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Acute infectious bursal disease in poultry: Immunological and molecular basis of antigenicity of a highly virulent strain

1 Dec 1996

Abstract excerpt

This study has confirmed, by the use of immunological and molecular tools, that the recent failures of vaccination against infectious bursal disease (IBD) encountered in Europe were not related to antigenic variation, but to increased virulence of the circulating IBD virus strains. Neutralizing monoclonal antibodies (Mabs) showed that the vaccines of intermediate virulence and the pathogenic strain 849VB had a...

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PMID: 18645896
DOI: 10.1080/03079459608419179

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