Article
Intra- and interpopulation genotype reconstruction from tagging SNPs.
Genome research - 1 Jan 2007
Paschou Peristera, Mahoney Michael W, Javed Asif, Kidd Judith R, Pakstis Andrew J, Gu Sheng, Kidd Kenneth K, Drineas Petros
Abstract excerpt
The optimal method to be used for tSNP selection, the applicability of a reference LD map to unassayed populations, and the scalability of these methods to genome-wide analysis, all remain subjects of debate. We propose novel, scalable matrix algorithms that address these issues and we evaluate them on genotypic data from 38 populations and four genomic regions (248 SNPs typed for approximately 2000 individuals)....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.