Article
Intra- and interpopulation genotype reconstruction from tagging SNPs.
Genome research - 1 Jan 2007
Paschou Peristera, Mahoney Michael W, Javed Asif, Kidd Judith R, Pakstis Andrew J, Gu Sheng, Kidd Kenneth K, Drineas Petros
Abstract excerpt
The optimal method to be used for tSNP selection, the applicability of a reference LD map to unassayed populations, and the scalability of these methods to genome-wide analysis, all remain subjects of debate. We propose novel, scalable matrix algorithms that address these issues and we evaluate t...
Topics
- Algorithms
- Chromosomes, Human, Pair 17
- Databases, Nucleic Acid
- Genotype
- Homeodomain Proteins
- Humans
- Linkage Disequilibrium
- Nerve Tissue Proteins
- Organic Anion Transport Protein 1
- Polymorphism, Single Nucleotide
- Receptors, Cell Surface
- Receptors, Neuropeptide