Article
Sap1 promotes the association of the replication fork protection complex with chromatin and is involved in the replication checkpoint in Schizosaccharomyces pombe.
Genetics - 1 Feb 2007
Noguchi Chiaki, Noguchi Eishi
Abstract excerpt
Sap1 is involved in replication fork pausing at rDNA repeats and functions during mating-type switching in Schizosaccharomyces pombe. These two roles are dependent on the ability of Sap1 to bind specific DNA sequences at the rDNA and mating-type loci, respectively. In S. pombe, Swi1 and Swi3 form the replication fork protection complex (FPC) and play important roles in the activation of the replication checkpoint...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
