Article
Isolation and characterization of temperature-sensitive mutations in the gene (rpb3) for subunit 3 of RNA polymerase II in the fission yeast Schizosaccharomyces pombe.
Molecular & general genetics : MGG - 1 Aug 1999
Mitobe J, Mitsuzawa H, Yasui K, Ishihama A
Abstract excerpt
Subunit 3 (Rpb3) of eukaryotic RNA polymerase II is a homologue of the alpha subunit of prokaryotic RNA polymerase, which plays a key role in subunit assembly of this complex enzyme by providing the contact surfaces for both beta and beta' subunits. Previously we demonstrated that the Schizosaccharomyces pombe Rpb3 protein forms a core subassembly together with Rpb2 (the beta homologue) and Rpb11 (the second...
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