Article
Genetic polymorphisms in the oxidative stress pathway and susceptibility to non-Hodgkin lymphoma.
Human genetics - 1 Apr 2007
Lan Qing, Zheng Tongzhang, Shen Min, Zhang Yawei, Wang Sophia S, Zahm Shelia H, Holford Theodore R, Leaderer Brian, Boyle Peter, Chanock Stephen
Abstract excerpt
Oxidative damage caused by reactive oxygen species (ROS) and other free radicals is involved in a number of pathological conditions including cancer. In a population-based case-control study of non-Hodgkin lymphoma (NHL) (n = 518 cases, 597 controls) among women in Connecticut, we analyzed one or more single nucleotide polymorphisms (SNPs) in ten candidate genes (AKR1A1, AKR1C1, AKR1C3, CYBA, GPX1, MPO, NOS2A,...
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