Article
Polymorphisms in DNA repair pathway genes, body mass index, and risk of non-Hodgkin lymphoma.
American journal of hematology - 1 Jul 2013
Chen Yingtai, Zheng Tongzhang, Lan Qing, Kim Christopher, Qin Qin, Foss Francine, Chen Xuezhong, Holford Theodore, Leaderer Brian, Boyle Peter, Wang Chengfeng, Dai Min, Liu Zhenjiang, Ma Shuangge, Chanock Stephen J, Rothman Nathaniel, Zhang Yawei
Abstract excerpt
We conducted a population-based case-control study in Connecticut women to test the hypothesis that genetic variations in DNA repair pathway genes may modify the relationship between body mass index (BMI) and risk of non-Hodgkin lymphoma (NHL). Compared to those with BMI <25, women with BMI ≥25 had significantly increased risk of NHL among women who carried BRCA1 (rs799917) CT/TT, ERCC2 (rs13181) AA, XRCC1...
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