Article
Genetic polymorphisms in oxidative stress pathway genes and modification of BMI and risk of non-Hodgkin lymphoma.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 May 2012
Kim Christopher, Zheng Tongzhang, Lan Qing, Chen Yingtai, Foss Francine, Chen Xuezhong, Holford Theodore, Leaderer Brian, Boyle Peter, Chanock Stephen J, Rothman Nathaniel, Zhang Yawei
Abstract excerpt
BACKGROUND: Being overweight and obese increases oxidative stress in the body. To test the hypothesis that genetic variations in oxidative stress pathway genes modify the relationship between body mass index (BMI) and risk of non-Hodgkin lymphoma (NHL), we conducted a population-based case-control study in Connecticut women. METHODS: Individuals who were overweight/obese (BMI ≥ 25) were compared with normal and...
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