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Article

Resequencing and association analysis of the SP110 gene in adult pulmonary tuberculosis.

Human genetics - 1 Apr 2007

Szeszko Jeffrey S, Healy Barry, Stevens Helen, Balabanova Yanina, Drobniewski Francis, Todd John A, Nejentsev Sergey

Abstract excerpt

Recently, the Intracellular pathogen resistance 1 (Ipr1) gene was shown to control susceptibility to Mycobacterium tuberculosis in mice. We examined whether common sequence variants of its human orthologue, the SP110 gene, are associated with susceptibility to tuberculosis in a human population. We resequenced SP110 exons in 96 individuals and identified new polymorphisms. Then, we combined our sequence and...

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Identifiers

PMID: 17149599
DOI: 10.1007/s00439-006-0293-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Resequencing and association analysis of the SP110 gene in adult pulmonary tuberculosis.PMID 17149599Read ↗

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Polymorphisms of SP110 are associated with both pulmonary and extra-pulmonary tuberculosis among the Vietnamese.Semantic proximity Read ↗

Genetic association study suggests a role for SP110 variants in lymph node tuberculosis but not pulmonary tuberculosis in north Indians.Semantic proximity Read ↗

SP110 as a novel susceptibility gene for Mycobacterium avium subspecies paratuberculosis infection in cattle.Semantic proximity Read ↗

Certain Polymorphisms in SP110 Gene Confer Susceptibility to Tuberculosis: A Comprehensive Review and Updated Meta-Analysis.Semantic proximity Read ↗

SP110 and PMP22 polymorphisms are associated with tuberculosis risk in a Chinese-Tibetan population.Semantic proximity Read ↗

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