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Article

Association of SP110 gene polymorphisms with susceptibility to tuberculosis in a Chinese population.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jul 2011

Liang Li, Zhao Yan-lin, Yue Jun, Liu Jian-fang, Han Min, Wang Hongxiu, Xiao Heping

Abstract excerpt

Development of tuberculosis is mediated by both environmental and genetic factors. The Ipr1 (intracellular pathogen resistance-1) gene has been identified at the sst1 (super-susceptibility to tuberculosis 1) locus on mouse chromosome 1. As Ipr1 plays a major role in mediating innate immunity in a mouse model of Mycobacterium tuberculosis infection, the human Ipr1 homologue, SP110 is a recognised candidate gene...

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Identifiers

PMID: 21397050
DOI: 10.1016/j.meegid.2011.02.017

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Association of SP110 gene polymorphisms with susceptibility to tuberculosis in a Chinese population.PMID 21397050Read ↗

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