Article
SP110 and PMP22 polymorphisms are associated with tuberculosis risk in a Chinese-Tibetan population.
Oncotarget - 4 Oct 2016
Ren Guoxia, You Jiangtao, Gong Xianfeng, Zhang Xiucheng, Zhao Lin, Wei Xianglan, Jin Tianbo, Chen Mingwei
Abstract excerpt
Susceptibility to tuberculosis (TB) is partially dependent on host genetic variability. SP110 and PMP22 are candidate genes identified in this study as associated with human susceptibility to TB. Here we performed an association analysis in a case-control study of a Tibetan population (217 cases and 383 controls). Using bioinformatics methods, we identified two SNPs in SP110 that may decrease susceptibility to TB...
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