Article
Polymorphisms in SP110 are not associated with pulmonary tuberculosis in Indonesians.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Aug 2012
Png Eileen, Alisjahbana Bachti, Sahiratmadja Edhyana, Marzuki Sangkot, Nelwan Ron, Adnan Iskandar, van de Vosse Esther, Hibberd Martin, van Crevel Reinout, Ottenhoff Tom H M, Seielstad Mark
Abstract excerpt
Despite being high transmissible, Mycobacterium tuberculosis (M. tuberculosis) infection causes active disease in only 5-10% of disease-susceptible individuals. This has instigated interest in studying potentially underlying genetic host factors and mechanisms in tuberculosis (TB). The recent identification of the Intracellular pathogen resistance 1 (Ipr1) gene, which plays a major role in controlling M....
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