Article
SP110 as a novel susceptibility gene for Mycobacterium avium subspecies paratuberculosis infection in cattle.
Journal of dairy science - 1 Dec 2010
Ruiz-Larrañaga O, Garrido J M, Iriondo M, Manzano C, Molina E, Montes I, Vazquez P, Koets A P, Rutten V P M G, Juste R A, Estonba A
Abstract excerpt
The intracellular pathogen resistance 1 (Ipr1) gene has been reported to play a role in mediating innate immunity in a mouse model of Mycobacterium tuberculosis infection, and polymorphisms of its human ortholog, SP110 nuclear body protein, have been suggested to be associated with tuberculosis....
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