Comprehensive characterization of IGHV3-21-expressing B-cell chronic lymphocytic leukemia: an Italian multicenter study.

doi:10.1182/blood-2006-10-051110

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Article

Comprehensive characterization of IGHV3-21-expressing B-cell chronic lymphocytic leukemia: an Italian multicenter study.

Blood - 1 Apr 2007

Bomben Riccardo, Dal Bo Michele, Capello Daniela, Benedetti Dania, Marconi Daniela, Zucchetto Antonella, Forconi Francesco, Maffei Rossana, Ghia Emanuela M, Laurenti Luca, Bulian Pietro, Del Principe Maria Ilaria, Palermo Giuseppe, Thorsélius Mia, Degan Massimo, Campanini Renato, Guarini Anna, Del Poeta Giovanni, Rosenquist Richard, Efremov Dimitar G, Marasca Roberto, Foà Robin, Gaidano Gianluca, Gattei Valter

Abstract excerpt

IGHV3-21-using chronic lymphocytic leukemia (CLL) is a distinct entity with restricted immunoglobulin gene features and poor prognosis and is more frequently encountered in Northern than Southern Europe. To further investigate this subset and its geographic distribution in the context of a country (Italy) with both continental and Mediterranean areas, 37 IGHV3-21 CLLs were collected out of 1076 cases enrolled by...

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Identifiers

PMID: 17148579
DOI: 10.1182/blood-2006-10-051110

Genes

TGFB2
VIPR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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