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Article

Brain tumors in S100beta-v-erbB transgenic rats.

Journal of neuropathology and experimental neurology - 1 Dec 2006

Ohgaki Hiroko, Kita Daisuke, Favereaux Alexandre, Huang Herve, Homma Taku, Dessen Pierre, Weiss William A, Kleihues Paul, Heppner Frank L

Abstract excerpt

We have established a line of transgenic rats expressing v-erbB, the viral form of epidermal growth factor receptor (EGFR), under transcriptional regulation of the S100beta promoter. Reverse transcriptase-polymerase chain reaction revealed highest transgene expression in the cerebellum followed by the cerebrum, ovary, and testis. Other organs, including the lung, heart, salivary gland, colon, liver, kidney, and...

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Source

Identifiers

PMID: 17146284
DOI: 10.1097/01.jnen.0000248544.28423.48

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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