Article
[Analysis of S100beta-v-erbB transgenic rats prone to brain tumors].
Brain and nerve = Shinkei kenkyu no shinpo - 1 Jul 2009
Yokoo Hideaki, Tanaka Yuko, Nobusawa Sumihito, Nakazato Yoichi, Ohgaki Hiroko
Abstract excerpt
We established a line of transgenic rats expressing v-erbB, the viral form of EGFR, under the transcriptional regulation of the S100beta promoter. This is the first transgenic rat model that spontaneously develops brain tumors. The rats maintained under conventional housing conditions until the o...
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