Article
Validation of positional candidates Rps6ka6 and Pou3f4 for a locus associated with skeletal muscle mass variability.
G3 (Bethesda, Md.) - 7 May 2024
Lekkos Konstantinos, Bhuiyan Afra A, Albloshi Abdullah M K, Brooks Paige M, Coate Thomas M, Lionikas Arimantas
Abstract excerpt
Genetic variability significantly contributes to individual differences in skeletal muscle mass; however, the specific genes involved in that process remain elusive. In this study, we examined the role of positional candidates, Rps6ka6 and Pou3f4, of a chromosome X locus, implicated in muscle mass variability in CFW laboratory mice. Histology of hindlimb muscles was studied in CFW male mice carrying the muscle...
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