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Article

Premature cellular senescence induced by pyocyanin, a redox-active Pseudomonas aeruginosa toxin.

Free radical biology & medicine - 1 Dec 2006

Muller Michael

Abstract excerpt

Pseudomonas aeruginosa is an important nosocomial pathogen that can cause acute and chronic infection, particularly of the respiratory system. Pyocyanin is a major P. aeruginosa virulence factor that displays redox activity and induces oxidative stress in cellular systems. The effect of pyocyanin on replicating human pulmonary epithelial (A549) cells was investigated. Cells were exposed to pyocyanin for 24 h and...

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Identifiers

PMID: 17145555
DOI: 10.1016/j.freeradbiomed.2006.09.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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