Pseudomonas toxin pyocyanin triggers autophagy: Implications for pathoadaptive mutations.

Abstract excerpt

Pseudomonas aeruginosa can establish life-long chronic infection in patients with cystic fibrosis by generating genetic loss-of-function mutations, which enhance fitness of the bacterium in the airways. However, the precise role of the pathoadaptive mutations in persistence in chronic airways infection remains largely unknown. Here we demonstrate that pyocyanin, a well-described P. aeruginosa virulence factor...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Autophagosomes
• Share to Autophagy
• Share to Bacterial Toxins