Article
Pseudomonas aeruginosa pyocyanin is critical for lung infection in mice.
Infection and immunity - 1 Jul 2004
Lau Gee W, Ran Huimin, Kong Fansheng, Hassett Daniel J, Mavrodi Dimitri
Abstract excerpt
Pseudomonas aeruginosa secretes copious amounts of the redox-active phenazine, pyocyanin (PCN), during cystic fibrosis lung infection. PCN has been shown to interfere with a variety of cellular processes in cultured lung epithelial cells. Here, by using two respiratory tract models of infection,...
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