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[Study on the association between catechol-O-methyltransferase gene polymorphisms and type 2 diabetes mellitus].

Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi - 1 Feb 2014

Xiu Liangchang, Liu Weiwei, Zhou Shancun, Lin Meihua, Ouyang Ping, Qin Jiheng, Zhao Xiaolei, Kong Danli, Rao Shaoqi, Ding Yuanlin

Abstract excerpt

OBJECTIVE: To evaluate the association between the two single nucleotide polymorphisms located in catechol-O-methyltransferase (COMT) gene and type 2 diabetes mellitus (T2DM)in Han population in Guangdong province. METHODS: Two tagSNPs (rs4646312 and rs4680) were picked out from COMT gene. Using the SNPscan(TM) Kit, SNP genotyping was then performed, in two cohorts, including 595 cases and 725 controls. Finally,...

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PMID: 24739563

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COMT

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