Article
Allorecognition of an HLA-A*01 aberrant allele by an HLA identical family member carrying the HLA-A*0101 allele.
Journal of immunology (Baltimore, Md. : 1950) - 15 Dec 2006
Almeciga Ingrid, Wang Zhigang Charles, Zúñiga Joaquin, Fernandez-Viña Marcelo, Clavijo Olga, Araujo Hugo, Romero Viviana, Henry John, Ferrone Soldano, Yunis Edmond J
Abstract excerpt
We identified and characterized an HLA-A1 aberrant allele (A*0118N) resulting from a novel molecular mechanism; this allele was present in an unusually informative family with a near identical parental HLA haplotype (c d) differing only by one nucleotide substitution in one HLA-A allele, A*0118N, of the maternal HLA haplotype (c) and not of the paternal HLA haplotype (a). Although serologic HLA typing showed a...
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