Article
Sequence of a new HLA-DR4 allele with an unusual residue at position 88 that does not seem to affect T-cell allo recognition.
Human immunology - 1 Nov 1996
Gebuhrer L, Adami N, Javaux F, Freidel A C, Jeannet M, Betuel H, Tiercy J M
Abstract excerpt
New HLA alleles can be identified by unorthodox patterns observed during low-resolution typing performed with sequence specific oligonucleotide probes (SSOP). One of the best examples is locus DRB1, where allelic subtypes are characterized by a combination of a limited number of residues located in three hypervariable regions of exon 2. HLA-DR oligotyping analysis of a female caucasoid bone marrow donor led to...
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