Article
Polymorphism of IL-1alpha, IL-1beta and IL-10 in patients with advanced ovarian cancer: results of a prospective study with 147 patients.
Gynecologic oncology - 1 Mar 2007
Ioana Braicu Elena, Mustea Alexander, Toliat Mohammad R, Pirvulescu Cristina, Könsgen Dominique, Sun Pengming, Nürnberg Peter, Lichtenegger Werner, Sehouli Jalid
Abstract excerpt
OBJECTIVE: Interleukin 1 (IL-1) and IL-10 are critically involved in tumorigenesis. We investigated polymorphisms of IL-1 and IL-10 genes in patients with ovarian cancer (OC). METHODS: In a prospective, case-control study 147 patients with OC and 129 patients without history of any malignancy (CG) were genotyped for IL-1 gene (IL-1alpha -889 T/C and IL-1beta -511 C/T) and IL-10 gene (IL-10 -1082 G/A, -819 C/T and...
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