Article
The prognostic value of IL10 and TNF alpha functional polymorphisms in premenopausal early-stage breast cancer patients.
BMC genetics - 26 Jun 2015
Korobeinikova Erika, Myrzaliyeva Dana, Ugenskiene Rasa, Raulinaityte Danguole, Gedminaite Jurgita, Smigelskas Kastytis, Juozaityte Elona
Abstract excerpt
BACKGROUND: Interleukin-10 and tumor necrosis factor α play an important role in breast carcinogenesis. Genes, encoding those two cytokines, contain single nucleotide polymorphisms, which are associated with differential levels of gene transcription. This study analyzes single nucleotide polymorphisms in interleukin 10 and tumor necrosis factor α genes and their contribution to breast cancer phenotype, lymph node...
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