Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prediction of the deleterious nsSNPs in ABCB transporters.

FEBS letters - 22 Dec 2006

Li Yanhong, Wang Yonghua, Li Yan, Yang Ling

Abstract excerpt

The non-synonymous SNPs (nsSNPs) in coding regions, neutral or deleterious, could lead to the alteration of the function or structure of proteins. We have developed the computational models to analyze the deleterious nsSNPs in the transporters and predict ones in ABCB (ATP-binding cassette B) transporters of interest. The RPLS (ridge partial least square) and LDA (linear discriminant analysis) methods were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Models, Biological
Share to Amino Acids
Share to ATP-Binding Cassette Transporters

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Computational Biology

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 17141228
DOI: 10.1016/j.febslet.2006.11.047

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prediction of the deleterious nsSNPs in ABCB transporters.PMID 17141228Read ↗

Phenotype prediction of non-synonymous single-nucleotide polymorphisms in human ATP-binding cassette transporter genes.Semantic proximity Read ↗

Non-neutral nonsynonymous single nucleotide polymorphisms in human ABC transporters: the first comparison of six prediction methods.Semantic proximity Read ↗

In silico analysis of nsSNPs in ABCB1 gene affecting breast cancer associated protein P-glycoprotein (P-gp).Semantic proximity Read ↗

Phenotype prediction of deleterious nonsynonymous single nucleotide polymorphisms in human alcohol metabolism-related genes: a bioinformatics study.Semantic proximity Read ↗

A bioinformatics approach for the phenotype prediction of nonsynonymous single nucleotide polymorphisms in human cytochromes P450.Semantic proximity Read ↗

Partition dataset according to amino acid type improves the prediction of deleterious non-synonymous SNPs.Semantic proximity Read ↗

A Comprehensive In Silico Analysis of the Functional and Structural Impact of Nonsynonymous SNPs in the ABCA1 Transporter GeneSemantic proximity Read ↗

Prediction of functional nonsynonymous single nucleotide polymorphisms in human G-protein-coupled receptors.Semantic proximity Read ↗

Profiling deleterious non-synonymous SNPs of smoker's gene CYP1A1.Semantic proximity Read ↗

Functional Characterization and In Silico Prediction Tools Improve the Pathogenicity Prediction of Novel Bile Acid Transporter Variants.Semantic proximity Read ↗

Potential dysfunctional effects of synonymous variants: Insights from an exhaustive in silico analysis of the ABCB4 gene.Semantic proximity Read ↗

Prediction of deleterious functional effects of non-synonymous single nucleotide polymorphisms in human nuclear receptor genes using a bioinformatics approach.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.