Article
Yeast flavohemoglobin protects against nitrosative stress and controls ferric reductase activity.
Redox report : communications in free radical research - 1 Jan 2006
Lewinska Anna, Bartosz Grzegorz
Abstract excerpt
The role of Saccharomyces cerevisiae flavohemoglobin (Yhb1) is controversial and far from understood. This study compares the effects of nitrosative and oxidative challenge on the yeast mutant lacking the YHB1 gene. Growth of the mutant was impaired by nitrosoglutathione and peroxynitrite, whereas increased sensitivity to reactive oxygen species was not observed. Increased levels of intracellular NO(*) after...
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