Article
A genetic analysis of nitric oxide-mediated signaling during chronological aging in the yeast.
Biogerontology - 1 Aug 2011
Lewinska Anna, Macierzynska Ewa, Grzelak Agnieszka, Bartosz Grzegorz
Abstract excerpt
In mammals, NO(•), a signaling molecule is implicated in the regulation of vasodilation, neurotransmission and immune response. It is believed that NO(•) is a signaling molecule also in unicellular organism like yeast and may be involved in the regulation of apoptosis and sporulation. It has been reported that NO(•) is produced during chronological aging (CA) leading to an increase of the superoxide level, which...
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