Article
The role of two putative nitroreductases, Frm2p and Hbn1p, in the oxidative stress response in Saccharomyces cerevisiae.
Yeast (Chichester, England) - 1 Feb 2010
de Oliveira Iuri Marques, Zanotto-Filho Alfeu, Moreira José Cláudio Fonseca, Bonatto Diego, Henriques João Antonio Pêgas
Abstract excerpt
The nitroreductase family is comprised of a group of FMN- or FAD-dependent enzymes that are able to metabolize nitrosubstituted compounds using the reducing power of NAD(P)H. These nitroreductases can be found in bacterial species and, to a lesser extent, in eukaryotes. There is little information on the biochemical functions of nitroreductases. Some studies suggest their possible involvement in the oxidative...
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