Article
Frequency of CTLA-4 gene CT60 polymorphism may not be affected by vitamin D receptor gene Bsm I polymorphism or HLA DR9 in autoimmune-related type 1 diabetes in the Japanese.
Annals of the New York Academy of Sciences - 1 Oct 2006
Kanazawa Yasuhiko, Motohashi Yoshiko, Yamada Satoru, Oikawa Yoichi, Shigihara Toshikatsu, Okubo Yoshiaki, Maruyama Taro, Shimada Akira
Abstract excerpt
One of the CTLA-4 SNPs, +6230G>A (CT60), has recently been reported to be related to susceptibility to type 1 diabetes and autoimmune thyroid disease. We have previously reported an association between acute-onset type 1 diabetes in Japanese and the Vitamin D receptor (VDR) gene Bsm I large B polymorphism, which is related to the Th1-type response. Moreover, we found a significant correlation between...
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