Article
[Association of CTLA-4 + 49A/G and CT60 gene polymorphism with type 1 diabetes and thyroid autoimmunity].
Zhonghua yi xue za zhi - 12 May 2009
Jin Ping, Xiang Bin, Lin Jian, Huang Gan, Zhou Wei-Dong, Zheng Chao, Chao Chen, Zhou Zhi-Guang
Abstract excerpt
OBJECTIVE: To investigate the association of CTLA-4 + 49A/G and CT60 gene polymorphisms with type 1 diabetes (T1DM) and thyroid autoimmunity. Subjects Three hundred thirty-two T1DM patients and 476 controls were recruited in the study. METHOD: The CTLA-4 + 49 A/G and CT60 polymorphisms of CTLA-4 gene were analyzed by polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP) method. Thyroid...
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