Article
Evidence for association between vitamin D receptor BsmI polymorphism and type 1 diabetes in Japanese.
Journal of autoimmunity - 1 Jun 2008
Shimada Akira, Kanazawa Yasuhiko, Motohashi Yoshiko, Yamada Satoru, Maruyama Taro, Ikegami Hiroshi, Awata Takuya, Kawasaki Eiji, Kobayashi Tetsuro, Nakanishi Koji, Kawabata Yumiko, Kurihara Susumu, Uga Miho, Tanaka Shoichiro
Abstract excerpt
Type 1 diabetes is considered to be T-helper 1 (Th1) type autoimmune disease. Because the vitamin D receptor is expressed on CD4+T cells and is known to affect cytokine responses, several groups have investigated the association between the vitamin D receptor gene BsmI polymorphism and type 1 diabetes. However, this issue is still controversial; therefore, we examined this gene polymorphism in a large number of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
