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Article

HLA class I epitope discovery in type 1 diabetes.

Annals of the New York Academy of Sciences - 1 Oct 2006

van Endert Peter, Hassainya Yousra, Lindo Vivian, Bach Jean-Marie, Blancou Philippe, Lemonnier François, Mallone Roberto

Abstract excerpt

Type 1 diabetes mellitus (T1DM) results from the destruction of beta cells by autoantigen-specific T cells. In the non-obese diabetic (NOD) mouse model, CD8+ T cells play an essential role in both the initial triggering of insulitis and its destructive phase, and proinsulin (PI) is one of the dominant target antigens (Ags). However, little is known about the beta cell epitopes presented by HLA class I molecules...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 17130554
DOI: 10.1196/annals.1375.030

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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