Article
Positive association between SIAT8B and schizophrenia in the Chinese Han population.
Schizophrenia research - 1 Feb 2007
Tao Ran, Li Chao, Zheng Yonglan, Qin Wei, Zhang Jing, Li Xingwang, Xu Yifeng, Shi Yong Yong, Feng Guoyin, He Lin
Abstract excerpt
The Sialyltransferase 8B gene (SIAT8B) is located at 15q26, a susceptibility region for both schizophrenia and bipolar disorder. The protein encoded by this gene has an important role in neural development and sialic acid synthesis on the neural cell adhesion molecule (NCAM). Previous research had indicated that the promoter region of SIAT8B is associated with schizophrenia in the Japanese population. To take...
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