Article
Association between ST8SIA2 and the Risk of Schizophrenia and Bipolar I Disorder across Diagnostic Boundaries.
PloS one - 1 Jan 2015
Yang So Yung, Huh Ik Soo, Baek Ji Hyun, Cho Eun-Young, Choi Mi Ji, Ryu Seunghyong, Kim Ji Sun, Park Taesung, Ha Kyooseob, Hong Kyung Sue
Abstract excerpt
BACKGROUND: Findings from family studies and recent genome-wide association studies have indicated overlap in the risk genes between schizophrenia and bipolar disorder (BD). After finding a linkage between the ST8SIA2 (ST8 alpha-N-acetyl-neuraminide alpha-2, 8-sicalyltransferase 2 gene) locus (15q26) and mixed families with schizophrenia and BD, several studies have reported a significant association between this...
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