Article
Association study between the TNXB locus and schizophrenia in a Japanese population.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Apr 2007
Tochigi Mamoru, Zhang Xuan, Ohashi Jun, Hibino Hiroyuki, Otowa Takeshi, Rogers Mark, Kato Tadafumi, Okazaki Yuji, Kato Nobumasa, Tokunaga Katsushi, Sasaki Tsukasa
Abstract excerpt
The chromosome 6p21-24 region, which contains the human leukocyte antigen (HLA) region, has been suggested as an important locus for a susceptibility gene for schizophrenia. Recently, a significant association between schizophrenia and the TNXB locus, located immediately telomeric of the NOTCH4 locus in the HLA region, was observed. Few studies have further investigated the region in schizophrenia. In the present...
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