Article
Pathophysiologic mechanisms in acquired aplastic anemia.
Hematology. American Society of Hematology. Education Program - 1 Jan 2006
Young Neal S
Abstract excerpt
Aplastic anemia, an unusual hematologic disease, is the paradigm of the human bone marrow failure syndromes. Absence of hematopoietic cells has been recognized from the characteristic morphology for a century; an immune pathophysiology has been inferred from improvement in blood counts with immunosuppressive therapy in the majority of patients. Molecular mechanisms underlying both T cell effector cells and the...
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