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Article

Aplastic anemia: Etiology, molecular pathogenesis, and emerging concepts.

European journal of haematology - 1 Dec 2018

Shallis Rory M, Ahmad Rami, Zeidan Amer M

Abstract excerpt

Aplastic anemia (AA) is rare disorder of bone marrow failure which if severe and not appropriately treated is highly fatal. AA is characterized by morphologic marrow features, namely hypocellularity, and resultant peripheral cytopenias. The molecular pathogenesis of AA is not fully understood, and a uniform process may not be the culprit across all cases. An antigen-driven and likely autoimmune dysregulated...

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Source

Identifiers

PMID: 30055055
DOI: 10.1111/ejh.13153

Genes

ASXL1
BCOR
PIGA
TERT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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