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Article

Computation of the posterior probability of linkage using 'high effect' genetic model priors.

Human heredity - 1 Jan 2008

Logue M W, Li Y

Abstract excerpt

OBJECTIVES: The posterior probability of linkage, or PPL, directly measures the probability that a disease gene is linked to a marker. By placing a Bayesian prior on the elements of the genetic model, it allows for an unknown genetic model without the inflationary effects of maximization. The standard technique uses essentially uniform priors over the elements of the penetrance vector. However, much of the...

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Identifiers

PMID: 18223315
DOI: 10.1159/000114163

Genes

PPL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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