Article
Cell cycle-specific and cell type-specific expression of Rb in the developing human retina.
Investigative ophthalmology & visual science - 1 Dec 2006
Lee Thomas C, Almeida Dena, Claros Nidia, Abramson David H, Cobrinik David
Abstract excerpt
PURPOSE: To define the pattern of Rb expression relative to cell cycle position and cell type in the developing human retina. METHODS: Cryosections of fetal week 11-18 retinas were immunostained for Rb and cell cycle- or cell type-specific markers. RESULTS: Rb was prominent in retinal progenitor cells (RPCs) expressing the cyclin D1, cyclin A, and cytoplasmic cyclin B markers of G1, S, and early to mid G2 phases,...
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