Article
Expression of developmentally defined retinal phenotypes in the histogenesis of retinoblastoma.
The American journal of pathology - 1 Aug 1992
Gonzalez-Fernandez F, Lopes M B, Garcia-Fernandez J M, Foster R G, De Grip W J, Rosemberg S, Newman S A, VandenBerg S R
Abstract excerpt
Retinoblastoma, the most common intraocular tumor of childhood, is a malignant neoplasm that arises during retinal development. The embryonal cell target for neoplastic transformation is not yet clearly defined. To better understand the histogenetic potential of this tumor, the expression of phot...
Topics
- Blotting, Northern
- Cell Differentiation
- Child, Preschool
- Eye Neoplasms
- Eye Proteins
- Female
- Humans
- Immunohistochemistry
- Infant
- Male
- Neuroglia
- Phenotype
- Photoreceptor Cells
- Retina
- Retinoblastoma
- Retinol-Binding Proteins
- Rod Opsins