Article
[Pharmacogenetics of anticancer drugs].
Pathologie-biologie - 1 Mar 2005
de Chaisemartin L, Loriot M-A
Abstract excerpt
Much progress has been made in treating human malignancies and there are now multiple treatment options with similar efficacy for nearly every type of cancer. However, the narrow therapeutic index of most chemotherapeutic agents and the severe consequences of undertreatment or overdosing have led to research molecular predictive factors of the toxicity and efficacy of cancer treatments. Genetic factors affecting...
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