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Article

Genetic variation in the nucleotide excision repair pathway and colorectal cancer risk.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Nov 2006

Berndt Sonja I, Platz Elizabeth A, Fallin M Daniele, Thuita Lucy W, Hoffman Sandra C, Helzlsouer Kathy J

Abstract excerpt

Nucleotide excision repair (NER) enzymes are critical for the removal of bulky DNA adducts caused by environmental carcinogens, such as heterocyclic amines and polycyclic aromatic hydrocarbons, which are found in two putative risk factors for colorectal cancer, tobacco smoke and meat cooked at hi...

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Identifiers

PMID: 17119055
DOI: 10.1158/1055-9965.EPI-06-0449

Genes

ERCC6
XPC

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-17119055-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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