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Article

A unique error signature for human DNA polymerase nu.

DNA repair - 4 Feb 2007

Arana Mercedes E, Takata Kei-ichi, Garcia-Diaz Miguel, Wood Richard D, Kunkel Thomas A

Abstract excerpt

Human DNA polymerase nu (pol nu) is one of three A family polymerases conserved in vertebrates. Although its biological functions are unknown, pol nu has been implicated in DNA repair and in translesion DNA synthesis (TLS). Pol nu lacks intrinsic exonucleolytic proofreading activity and discriminates poorly against misinsertion of dNTP opposite template thymine or guanine, implying that it should copy DNA with...

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Identifiers

PMID: 17118716
DOI: 10.1016/j.dnarep.2006.09.012
PMCID: PMC1950682

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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