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Article

A role for Xrcc2 in the early stages of mouse development.

DNA repair - 4 Feb 2007

Adam Julie, Deans Bryan, Thacker John

Abstract excerpt

Xrcc2 is one of a family of five Rad51-like genes with important roles in the repair of DNA damage by homologous recombination (HR) in mammals. We have shown previously that loss of Xrcc2 in mice results in severe but variable developmental defects and embryonic lethality, potentially linked to excessive apoptosis. To look at the causes of lethality, and possibly to allow Xrcc2-/- mice to survive to birth, we...

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Identifiers

PMID: 17116431
DOI: 10.1016/j.dnarep.2006.10.024

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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