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Article

Susceptibility groups for Alzheimer's disease (OPTIMA cohort): integration of gene variants and biochemical factors.

Mechanisms of ageing and development - 1 Jan 2007

Corder Elizabeth H, Beaumont Helen

Abstract excerpt

Information on gene variants and blood levels (APOE, BCHE-K, TF-C2, HFE-D, HFE-Y, ACE I/D, AR1; homocysteine, folate and vitamin B(12)) is available for participants in the Oxford Project to Investigate Memory and Ageing (OPTIMA) cohort (n=575). This information identified four risk sets for Alzheimer's disease (AD) using grade of membership analysis (GoM). Graded membership scores that relate individuals to each...

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Source

Identifiers

PMID: 17116317
DOI: 10.1016/j.mad.2006.11.014

Genes

HFE
ACE
APOE
BCHE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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