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Mild Cognitive Impairment is not a Valid Concept and Should be Replaced by a More Restrictive, Biologically Validated Class, Named Mild Cognitive Dysfunctions (MCD): A Nomothetic Network Approach

2021-06-21

Abstract excerpt

<h4>Background: </h4> No studies have examined whether interactions between the apolipoprotein E4 (ApoE4) allele and peripheral biomarkers, hypertension, and type 2 diabetes mellitus (T2DM) may impact the neurocognitive, behavioral and social dysfunctions in amnestic mild cognitive impairment (aMCI) and Alzheimer disease (AD). <h4>Aims:</h4> To clinically define and biologically validate a subgroup of aMCI subject...

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Literature Corpus work: edfdb900-9469-5544-9d06-7f196f7cf203
DOI: 10.20944/preprints202106.0513.v1

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