Article

Mild cognitive impairment is not a valid concept and should be replaced by a more restrictive, biologically validated class, named Mild Cognitive Dysfunctions (MCD): a nomothetic network approach

2021-06-21

Abstract excerpt

<h4>Background</h4> No studies have examined whether interactions between the apolipoprotein E4 (ApoE4) allele and peripheral biomarkers, hypertension, and type 2 diabetes mellitus (T2DM) may impact the neurocognitive, behavioral and social dysfunctions in amnestic mild cognitive impairment (aMCI) and Alzheimer disease (AD). <h4>Aims</h4> To clinically define and biologically validate a subgroup of aMCI subjects t...

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Literature Corpus work: 1ffc3ad6-24e2-5422-8753-810072aa7f54
DOI: 10.1101/2021.06.20.21259193

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