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Article

Distinct co-regulation of endogenous versus transfected MITF-dependent tyrosinase promoter.

Folia biologica - 1 Jan 2006

Sestáková B, Vachtenheim J

Abstract excerpt

The tissue-specific control of gene activation in melanocytes is directed by the microphthalmia-associated transcription factor (MITF), a master regulator of melanocyte development and differentiation. Tyrosinase is a rate-limiting enzyme in melanin biosynthesis and a prototypic MITF target. While the expression of tyrosinase is restricted to pigmented cells, the transfected tyrosinase promoter is active in a...

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Source

Identifiers

PMID: 17116288

Genes

MITF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Distinct co-regulation of endogenous versus transfected MITF-dependent tyrosinase promoter.PMID 17116288Read ↗

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