Development and characterization of polarized primary cultures of rat intrahepatic bile duct epithelial cells.

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Article

Development and characterization of polarized primary cultures of rat intrahepatic bile duct epithelial cells.

Laboratory investigation; a journal of technical methods and pathology - 1 Jan 1996

Vroman B, LaRusso N F

Abstract excerpt

The study of intrahepatic bile duct epithelial cells (i.e., cholangiocytes) has been limited by the lack of a polarized in vitro model that allows easy access to both apical and basolateral cell surfaces. Therefore, we developed a cell line of polarized normal rat cholangiocytes (NRCs) and establ...

Topics

Animals
Bile Ducts, Intrahepatic
Cell Culture Techniques
Cell Polarity
Collagen
Culture Media
Epithelial Cells
Epithelium
Image Processing, Computer-Assisted
Male
Phenotype
Rats
Rats, Inbred F344
Receptors, Somatostatin

Source

Open in PubMed

Identifiers

PMID: 8569194

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8569194-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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