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Article

The structural and functional polarity of the hepatic human/rat hybrid WIF-B is a stable and dominant trait.

Hepatology (Baltimore, Md.) - 1 Oct 1999

Bender V, Bravo P, Decaens C, Cassio D

Abstract excerpt

WIF-B cells were generated previously to obtain a good in vitro model expressing the structural and functional polarity of hepatocytes. Here we tested the stability and the strength of the WIF-B polarized phenotype. WIF-B cells stayed polarized and formed functional bile canaliculi even after 3 months in culture or after injection in nude mice and culture of the resulting tumors. WIF-B was subcloned and 10,000...

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Identifiers

PMID: 10498653
DOI: 10.1002/hep.510300436

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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